staff:tamas.beke-somfai

Tamás Beke-Somfai

Research group	Beke-Somfai Lab: Biomolecular Self-Assembly
Role	Group leader
MTMT	10027455
ORCID	0000-0002-4788-3758

Curriculum Vitae

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List of publications

2026
2025
2024
2023
2022
2021
2020
2019
2018
2017
2016
2015
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2013
2012
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2002

Click Chemistry for Peptidomimetic Applications (2026)
Flavia Ferrara, Tamás Beke-Somfai, Morten Grøtli, Nina Kann Topics in Heterocyclic Chemistry
Springer Berlin Heidelberg DOI:10.1007/7081_2026_106
Parametrization of β 3 -Peptides for Coarse-Grained Molecular Dynamics Simulations (2026)
O. Pavela, A. Wacha, T. Beke-Somfai, A. K. Sieradzan Journal of Chemical Information and Modeling
American Chemical Society (ACS) DOI:10.1021/acs.jcim.5c03108
An ATP‐Mediated Antibiotic β‐Peptide Nanofiber That Kills Multidrug‐Resistant Bacteria via a Multistage Mechanism (2026)
Sohini Chakraborty, Kamal el Battioui, Dániel Molnár, Bálint Jezsó, Lejla Daruka, Tasvilla Sonallya, Tünde Juhász, Rita Hirmondó, Imola Cs. Szigyártó, Loránd Románszki, Natália Tőkési, Daniel Pinkas, Eszter Házy, Olivér Pavela, Andrea Bodor, Zoltán Varga, István Mándity, Mihály Kovács, Csaba Pál, Kata Horváti, Judit Tóth, Tamás Beke‐Somfai Advanced Science
Wiley DOI:10.1002/advs.202522269
Sequence‐Driven Modulation of the Multistage Self‐Assembly Process in Lamellin‐Type β‐Peptides (2026)
Imola Cs. Szigyártó, Kristóf Ferentzi, András Wacha, Kamal el Battioui, Olivér Pavela, Vignesh Udyavara Nagaraj, Viktor Farkas, Tamás Beke‐Somfai Aggregate 7/2
Wiley DOI:10.1002/agt2.70282

Supramolecular Complexes of Ultrashort Cationic Lipopeptides with Cyclodextrins: Improved Selectivity and Therapeutic Potential (2025)
Chiara Bellini, Unai Atxabal, Szilvia Bősze, Orsolya Dobay, Andrea Horváth, Imola Cs. Szigyártó, Tamás Beke‐Somfai, Jesús Jiménez‐Barbero, István Puskás, Kata Horváti Aggregate 6/4
Wiley DOI:10.1002/agt2.741
Biophysical Profiling of Protein Corona on Red Blood Cell-Derived Extracellular Vesicles (REVs): Linear Dichroism and Microfluidic Resistive Pulse Sensing Separate Surface Clearing from Vesicle Disruption (2025)
Tasvilla Sonallya, Anikó Gaál, Imola Cs. Szigyártó, Zoltán Varga, Tamás Beke-Somfai Methods in Molecular Biology p213-223
Springer US DOI:10.1007/978-1-0716-4434-8_14
ATR-Infrared Spectroscopy and Acoustic Sensing in Characterization of Blood and Pancreatic Ductal Adenocarcinoma-Derived Extracellular Vesicles (2025)
Imola Cs. Szigyártó, Priyanka Singh, Tasvilla Sonallya, Loránd Románszki, Judith Mihály, Zoltán Wiener, Tímea Bebesi, Gábor Mészáros, Zsófia Keresztes, Michael Thompson, Zoltán Varga, Tamás Beke-Somfai Methods in Molecular Biology p225-238
Springer US DOI:10.1007/978-1-0716-4434-8_15
Charge and length dependent build-up of environment sensitive lamellin β-peptides (2025)
Sohini Chakraborty, Kamal el Battioui, Tasvilla Sonallya, Imola Cs. Szigyártó, Kata Horváti, Zoltán Varga, Tünde Juhász, Tamás Beke-Somfai Physical Chemistry Chemical Physics 27/16 p8540-8551
Royal Society of Chemistry (RSC) DOI:10.1039/d4cp04561k
Betaine‐Conjugated ß‐Peptide Foldamers: Influence of Quaternary Charge on Self‐Organization and MorphologyFormation (2025)
Nikolett Varró, Eszter Erdei, Dóra Bogdán, Eszter Kalydi, Ruth Deme, Balázs Balogh, Imola Cs. Szigyártó, Tamás Beke‐Somfai, Zoltán Varga, Pál Szabó, István M. Mándity ChemistryOpen 14/12
Wiley DOI:10.1002/open.202500340
Residual flexibility in the topologically constrained multivalent complex between the <scp>GKAP</scp> scaffold and <scp>LC</scp> 8 hub proteins (2025)
Eszter Nagy‐Kanta, Zsófia E. Kálmán, Helena Tossavainen, Tünde Juhász, Fanni Farkas, József Hegedüs, Melinda Keresztes, Tamás Beke‐Somfai, Zoltán Gáspári, Perttu Permi, Bálint Péterfia The FEBS Journal 293/1 p76-95
Wiley DOI:10.1111/febs.70219

Recent Developments in the Ruthenium‐Catalyzed Azide Alkyne Cycloaddition (RuAAC) Reaction (2024)
Flavia Ferrara, Tamás Beke‐Somfai, Nina Kann European Journal of Organic Chemistry 27/25
Wiley DOI:10.1002/ejoc.202400113
Mapping of the Lipid-Binding Regions of the Antifungal Protein NFAP2 by Exploiting Model Membranes (2024)
Olivér Pavela, Tünde Juhász, Liliána Tóth, András Czajlik, Gyula Batta, László Galgóczy, Tamás Beke-Somfai Journal of Chemical Information and Modeling 64/16 p6557-6569
American Chemical Society (ACS) DOI:10.1021/acs.jcim.4c00229
Functional contribution of condensate formation by single-stranded DNA binding protein (SSB) to bacterial genome maintenance (2024)
Peter Ecsédi, János Pálinkás, Zoltán Kovács, Gábor Harami, Tunde Juhasz, Balint Jezso, David Erfalvy, Lamiya Mahmudova, Eszter Házy, Tamas Beke-Somfai, Mihaly Kovacs Biophysical Journal 123/3 p79a-80a
Elsevier BV DOI:10.1016/j.bpj.2023.11.547
Categorizing interaction modes of antimicrobial peptides with extracellular vesicles: Disruption, membrane trespassing, and clearance of the protein corona (2025)
Tasvilla Sonallya, Tünde Juhász, Imola Cs. Szigyártó, Kinga Ilyés, Priyanka Singh, Delaram Khamari, Edit I. Buzás, Zoltán Varga, Tamás Beke-Somfai Journal of Colloid and Interface Science 679 p496-509
Elsevier BV DOI:10.1016/j.jcis.2024.09.244
Peptide‐Based Assemblies for Supercapacitor Applications (2024)
Sohini Chakraborty, Kamal el Battioui, Tamás Beke-Somfai Small Science 4/3
Wiley DOI:10.1002/smsc.202300217
In situ captured antibacterial action of membrane-incising peptide lamellae (2024)
Kamal el Battioui, Sohini Chakraborty, András Wacha, Dániel Molnár, Mayra Quemé-Peña, Imola Cs. Szigyártó, Csenge Lilla Szabó, Andrea Bodor, Kata Horváti, Gergő Gyulai, Szilvia Bősze, Judith Mihály, Bálint Jezsó, Loránd Románszki, Judit Tóth, Zoltán Varga, István Mándity, Tünde Juhász, Tamás Beke-Somfai Nature Communications 15/1
Springer Science and Business Media LLC DOI:10.1038/s41467-024-47708-4
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches (2024)
Joshua A. Welsh, Deborah C. I. Goberdhan, Lorraine O'Driscoll, Edit I. Buzas, Cherie Blenkiron, Benedetta Bussolati, Houjian Cai, Dolores Di Vizio, Tom A. P. Driedonks, Uta Erdbrügger, Juan M. Falcon‐Perez, Qing‐Ling Fu, Andrew F. Hill, Metka Lenassi, Sai Kiang Lim, Mỹ G. Mahoney, Sujata Mohanty, Andreas Möller, Rienk Nieuwland, Takahiro Ochiya, Susmita Sahoo, Ana C. Torrecilhas, Lei Zheng, Andries Zijlstra, Sarah Abuelreich, Reem Bagabas, Paolo Bergese, Esther M. Bridges, Marco Brucale, Dylan Burger, Randy P. Carney, Emanuele Cocucci, Rossella Crescitelli, Edveena Hanser, Adrian L. Harris, Norman J. Haughey, An Hendrix, Alexander R. Ivanov, Tijana Jovanovic‐Talisman, Nicole A. Kruh‐Garcia, Vroniqa Ku'ulei‐Lyn Faustino, Diego Kyburz, Cecilia Lässer, Kathleen M. Lennon, Jan Lötvall, Adam L. Maddox, Elena S. Martens‐Uzunova, Rachel R. Mizenko, Lauren A. Newman, Andrea Ridolfi, Eva Rohde, Tatu Rojalin, Andrew Rowland, Andras Saftics, Ursula S. Sandau, Julie A. Saugstad, Faezeh Shekari, Simon Swift, Dmitry Ter‐Ovanesyan, Juan P. Tosar, Zivile Useckaite, Francesco Valle, Zoltan Varga, Edwin van der Pol, Martijn J. C. van Herwijnen, Marca H. M. Wauben, Ann M. Wehman, Sarah Williams, Andrea Zendrini, Alan J. Zimmerman, , Clotilde Théry, Kenneth W. Witwer Journal of Extracellular Vesicles 13/2
Wiley DOI:10.1002/jev2.12404

Comparative Study of Molecular Mechanics Force Fields for β-Peptidic Foldamers: Folding and Self-Association (2023)
András Wacha, Zoltán Varga, Tamás Beke-Somfai Journal of Chemical Information and Modeling 63/12 p3799-3813
American Chemical Society (ACS) DOI:10.1021/acs.jcim.3c00175
The Mechanism of Antimicrobial Small-Cationic Peptides from Coarse-Grained Simulations (2023)
Ezequiel N. Frigini, Rodolfo D. Porasso, Tamás Beke-Somfai, José Javier López Cascales, Ricardo D. Enriz, Sergio Pantano Journal of Chemical Information and Modeling 63/21 p6877-6889
American Chemical Society (ACS) DOI:10.1021/acs.jcim.3c01348
Removal and identification of external protein corona members from RBC‐derived extracellular vesicles by surface manipulating antimicrobial peptides (2023)
Priyanka Singh, Imola Cs. Szigyártó, Maria Ricci, Anikó Gaál, Mayra Maritza Quemé‐Peña, Diána Kitka, Lívia Fülöp, Lilla Turiák, László Drahos, Zoltán Varga, Tamás Beke‐Somfai Journal of Extracellular Biology 2/3
Wiley DOI:10.1002/jex2.78
Unique thermophoretic behavior of supramolecular assemblies of cationic antimicrobial peptides with anionic small molecule agents (2023)
Tünde Juhász, Mayra Quemé-Peña, Tamás Beke-Somfai Journal of Molecular Liquids 386 p122513
Elsevier BV DOI:10.1016/j.molliq.2023.122513

Neuronal-specific septin-3 binds Atg8/LC3B, accumulates and localizes to autophagosomes during induced autophagy (2022)
Vilmos Tóth, Henrietta Vadászi, Lilla Ravasz, Dániel Mittli, Dominik Mátyás, Tamás Molnár, András Micsonai, Tamás Szaniszló, Péter Lőrincz, Réka Á. Kovács, Tünde Juhász, Tamás Beke-Somfai, Gábor Juhász, Balázs András Györffy, Katalin A. Kékesi, József Kardos Cellular and Molecular Life Sciences 79/9
Springer Science and Business Media LLC DOI:10.1007/s00018-022-04488-8
Single-particle detection of native SARS-CoV-2 virions by microfluidic resistive pulse sensing (2022)
Zoltán Varga, Mónika Madai, Gábor Kemenesi, Tamás Beke-Somfai, Ferenc Jakab Colloids and Surfaces B: Biointerfaces 218 p112716
Elsevier BV DOI:10.1016/j.colsurfb.2022.112716
Storage conditions determine the characteristics of red blood cell derived extracellular vesicles (2022)
Tímea Bebesi, Diána Kitka, Anikó Gaál, Imola Csilla Szigyártó, Róbert Deák, Tamás Beke-Somfai, Kitti Koprivanacz, Tünde Juhász, Attila Bóta, Zoltán Varga, Judith Mihály Scientific Reports 12/1
Springer Science and Business Media LLC DOI:10.1038/s41598-022-04915-7
Stimuli-Responsive Membrane Anchor Peptide Nanofoils for Tunable Membrane Association and Lipid Bilayer Fusion (2022)
Vignesh Udyavara Nagaraj, Tünde Juhász, Mayra Quemé-Peña, Imola Cs. Szigyártó, Dóra Bogdán, András Wacha, Judith Mihály, Loránd Románszki, Zoltán Varga, Joakim Andréasson, István Mándity, Tamás Beke-Somfai ACS Applied Materials & Interfaces 14/50 p55320-55331
American Chemical Society (ACS) DOI:10.1021/acsami.2c11946

PmlBeta: A PyMOL extension for building <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline" id="d1e66" altimg="si50.svg"> <mml:mi>β</mml:mi> </mml:math> -amino acid insertions and <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline" id="d1e71" altimg="si50.svg"> <mml:mi>β</mml:mi> </mml:math> -peptide sequences (2021)
András Wacha, Tamás Beke-Somfai SoftwareX 13 p100654
Elsevier BV DOI:10.1016/j.softx.2020.100654
New short cationic antibacterial peptides. Synthesis, biological activity and mechanism of action (2021)
Beatriz Lima, Maria Ricci, Adriana Garro, Tünde Juhász, Imola Csilla Szigyártó, Zita I. Papp, Gabriela Feresin, Jose Garcia de la Torre, Javier Lopez Cascales, Lívia Fülöp, Tamás Beke-Somfai, Ricardo D. Enriz Biochimica et Biophysica Acta (BBA) - Biomembranes 1863/10 p183665
Elsevier BV DOI:10.1016/j.bbamem.2021.183665
Quorum Sensing Pseudomonas Quinolone Signal Forms Chiral Supramolecular Assemblies With the Host Defense Peptide LL-37 (2021)
Ferenc Zsila, Maria Ricci, Imola Csilla Szigyártó, Priyanka Singh, Tamás Beke-Somfai Frontiers in Molecular Biosciences 8
Frontiers Media SA DOI:10.3389/fmolb.2021.742023
Structural Water Stabilizes Protein Motifs in Liquid Protein Phase: The Folding Mechanism of Short β-Sheets Coupled to Phase Transition (2021)
Dóra Papp, Imola Csilla Szigyártó, Bengt Nordén, András Perczel, Tamás Beke-Somfai International Journal of Molecular Sciences 22/16 p8595
MDPI AG DOI:10.3390/ijms22168595
Interplay between membrane active host defense peptides and heme modulates their assemblies and in vitro activity (2021)
Tünde Juhász, Mayra Quemé-Peña, Bence Kővágó, Judith Mihály, Maria Ricci, Kata Horváti, Szilvia Bősze, Ferenc Zsila, Tamás Beke-Somfai Scientific Reports 11/1
Springer Science and Business Media LLC DOI:10.1038/s41598-021-97779-2
Controlling Peptide Function by Directed Assembly Formation: Mechanistic Insights Using Multiscale Modeling on an Antimicrobial Peptide–Drug–Membrane System (2021)
Gergely Kohut, Tünde Juhász, Mayra Quemé-Peña, Szilvia Erika Bősze, Tamás Beke-Somfai ACS Omega 6/24 p15756-15769
American Chemical Society (ACS) DOI:10.1021/acsomega.1c01114
Membrane Association Modes of Natural Anticancer Peptides: Mechanistic Details on Helicity, Orientation, and Surface Coverage (2021)
Mayra Quemé-Peña, Tünde Juhász, Gergely Kohut, Maria Ricci, Priyanka Singh, Imola Cs. Szigyártó, Zita I. Papp, Lívia Fülöp, Tamás Beke-Somfai International Journal of Molecular Sciences 22/16 p8613
MDPI AG DOI:10.3390/ijms22168613
3 Ruthenium-Catalyzed Azide–Alkyne Cycloaddition (RuAAC) (2022)
A. J. Paterson, T. Beke-Somfai, N. Kann Click Chemistry
Georg Thieme Verlag KG DOI:10.1055/sos-sd-235-00118

ConjuPepDB: a database of peptide–drug conjugates (2020)
Balázs Balogh, Márton Ivánczi, Bilal Nizami, Tamás Beke-Somfai, István M Mándity Nucleic Acids Research 49/D1 pD1102-D1112
Oxford University Press (OUP) DOI:10.1093/nar/gkaa950
Human host-defense peptide LL-37 targets stealth siderophores (2020)
Ferenc Zsila, Tamás Beke-Somfai Biochemical and Biophysical Research Communications 526/3 p780-785
Elsevier BV DOI:10.1016/j.bbrc.2020.03.162
Michler’s hydrol blue elucidates structural differences in prion strains (2020)
Yiling Xiao, Sandra Rocha, Catherine C. Kitts, Anna Reymer, Tamás Beke-Somfai, Kendra K. Frederick, Bengt Nordén Proceedings of the National Academy of Sciences 117/47 p29677-29683
Proceedings of the National Academy of Sciences DOI:10.1073/pnas.2001732117
Revealing Molecular-Level Interaction between a Polymeric Drug and Model Membrane Via Sum Frequency Generation and Microfluidics (2020)
Chu Wang, Yongsheng Luo, Xu Li, Furong Zhang, Feng Wang, Xiaofeng Han, Ting Wang, Tamás Beke-Somfai, Xiaolin Lu Langmuir 36/6 p1615-1622
American Chemical Society (ACS) DOI:10.1021/acs.langmuir.9b03676
Anionic food color tartrazine enhances antibacterial efficacy of histatin-derived peptide DHVAR4 by fine-tuning its membrane activity (2020)
Maria Ricci, Kata Horváti, Tünde Juhász, Imola Szigyártó, György Török, Fanni Sebák, Andrea Bodor, László Homolya, Judit Henczkó, Bernadett Pályi, Tamás Mlinkó, Judith Mihály, Bilal Nizami, Zihuayuan Yang, Fengming Lin, Xiaolin Lu, Loránd Románszki, Attila Bóta, Zoltán Varga, Szilvia Bősze, Ferenc Zsila, Tamás Beke-Somfai Quarterly Reviews of Biophysics 53
Cambridge University Press (CUP) DOI:10.1017/s0033583520000013
Membrane Active Peptides Remove Surface Adsorbed Protein Corona From Extracellular Vesicles of Red Blood Cells (2020)
Priyanka Singh, Imola Cs. Szigyártó, Maria Ricci, Ferenc Zsila, Tünde Juhász, Judith Mihály, Szilvia Bősze, Éva Bulyáki, József Kardos, Diána Kitka, Zoltán Varga, Tamás Beke-Somfai Frontiers in Chemistry 8
Frontiers Media SA DOI:10.3389/fchem.2020.00703
Old Polyanionic Drug Suramin Suppresses Detrimental Cytotoxicity of the Host Defense Peptide LL-37 (2020)
Mayra Quemé-Peña, Maria Ricci, Tünde Juhász, Kata Horváti, Szilvia Bősze, Beáta Biri-Kovács, Bálint Szeder, Ferenc Zsila, Tamás Beke-Somfai ACS Pharmacology & Translational Science 4/1 p155-167
American Chemical Society (ACS) DOI:10.1021/acsptsci.0c00155
Membrane active Janus-oligomers of β3-peptides (2020)
Imola Cs. Szigyártó, Judith Mihály, András Wacha, Dóra Bogdán, Tünde Juhász, Gergely Kohut, Gitta Schlosser, Ferenc Zsila, Vlada Urlacher, Zoltán Varga, Ferenc Fülöp, Attila Bóta, István Mándity, Tamás Beke-Somfai Chemical Science 11/26 p6868-6881
Royal Society of Chemistry (RSC) DOI:10.1039/d0sc01344g
Chiral 1,5-disubstituted 1,2,3-triazoles – versatile tools for foldamers and peptidomimetic applications (2020)
Anna Said Stålsmeden, Andrew J. Paterson, Imola Cs. Szigyártó, Linda Thunberg, Johan R. Johansson, Tamás Beke-Somfai, Nina Kann Organic & Biomolecular Chemistry 18/10 p1957-1967
Royal Society of Chemistry (RSC) DOI:10.1039/d0ob00168f

Interaction of antitubercular drug candidates with α1-acid glycoprotein produced in pulmonary granulomas (2020)
Ferenc Zsila, Szilvia Bősze, Tamás Beke-Somfai International Journal of Biological Macromolecules 147 p1318-1327
Elsevier BV DOI:10.1016/j.ijbiomac.2019.10.096
Detection and phenotyping of extracellular vesicles by size exclusion chromatography coupled with on-line fluorescence detection (2019)
Diána Kitka, Judith Mihály, Jean-Luc Fraikin, Tamás Beke-Somfai, Zoltán Varga Scientific Reports 9/1
Springer Science and Business Media LLC DOI:10.1038/s41598-019-56375-1
Disorder-to-helix conformational conversion of the human immunomodulatory peptide LL-37 induced by antiinflammatory drugs, food dyes and some metabolites (2019)
Ferenc Zsila, Gergely Kohut, Tamás Beke-Somfai International Journal of Biological Macromolecules 129 p50-60
Elsevier BV DOI:10.1016/j.ijbiomac.2019.01.209
Felgyorsított evolúció – A 2018-as kémiai Nobel-díj (2019)
Tamás Beke-Somfai Magyar Tudomány
Akademiai Kiado Zrt. DOI:10.1556/2065.180.2019.9.13
Improved Modeling of Peptidic Foldamers Using a Quantum Chemical Parametrization Based on Torsional Minimum Energy Path Matching (2019)
András Wacha, Tamás Beke‐Somfai, Tibor Nagy ChemPlusChem 84/7 p927-941
Wiley DOI:10.1002/cplu.201900180
The molecular mechanism of structural changes in the antimicrobial peptide CM15 upon complex formation with drug molecule suramin: a computational analysis (2019)
Gergely Kohut, Adam Sieradzan, Ferenc Zsila, Tünde Juhász, Szilvia Bősze, Adam Liwo, Sergey A. Samsonov, Tamás Beke-Somfai Physical Chemistry Chemical Physics 21/20 p10644-10659
Royal Society of Chemistry (RSC) DOI:10.1039/c9cp00471h
Revealing Interfacial Lipid Hydrolysis Catalyzed by Phospholipase A1 at Molecular Level via Sum Frequency Generation Vibrational Spectroscopy and Fluorescence Microscopy (2019)
Feng Wang, Xu Li, Furong Zhang, Xiaoyang Liu, Pengcheng Hu, Tamás Beke-Somfai, Xiaolin Lu Langmuir 35/39 p12831-12838
American Chemical Society (ACS) DOI:10.1021/acs.langmuir.9b02284
Nanoerythrosomes tailoring: Lipid induced protein scaffolding in ghost membrane derived vesicles (2020)
Róbert Deák, Judith Mihály, Imola Cs. Szigyártó, Tamás Beke-Somfai, Lilla Turiák, László Drahos, András Wacha, Attila Bóta, Zoltán Varga Materials Science and Engineering: C 109 p110428
Elsevier BV DOI:10.1016/j.msec.2019.110428
FoldamerDB: a database of peptidic foldamers (2019)
Bilal Nizami, Dorottya Bereczki-Szakál, Nikolett Varró, Kamal el Battioui, Vignesh U Nagaraj, Imola Cs Szigyártó, István Mándity, Tamás Beke-Somfai Nucleic Acids Research
Oxford University Press (OUP) DOI:10.1093/nar/gkz993
Manipulating Active Structure and Function of Cationic Antimicrobial Peptide CM15 with the Polysulfonated Drug Suramin: A Step Closer to in Vivo Complexity (2019)
Mayra Quemé‐Peña, Tünde Juhász, Judith Mihály, Imola Cs. Szigyártó, Kata Horváti, Szilvia Bősze, Judit Henczkó, Bernadett Pályi, Csaba Németh, Zoltán Varga, Ferenc Zsila, Tamás Beke‐Somfai ChemBioChem 20/12 p1578-1590
Wiley DOI:10.1002/cbic.201800801

Heparin and Heparan Sulfate Binding of the Antiparasitic Drug Imidocarb: Circular Dichroism Spectroscopy, Isothermal Titration Calorimetry, and Computational Studies (2018)
Ferenc Zsila, Tünde Juhász, Gergely Kohut, Tamás Beke-Somfai The Journal of Physical Chemistry B 122/6 p1781-1791
American Chemical Society (ACS) DOI:10.1021/acs.jpcb.7b08876
The lipid mediator lysophosphatidic acid induces folding of disordered peptides with basic amphipathic character into rare conformations (2018)
Tünde Juhász, Judith Mihály, Gergely Kohut, Csaba Németh, Károly Liliom, Tamás Beke-Somfai Scientific Reports 8/1
Springer Science and Business Media LLC DOI:10.1038/s41598-018-32786-4
Molecular dynamics-based model of VEGF-A and its heparin interactions (2018)
Urszula Uciechowska-Kaczmarzyk, Sándor Babik, Ferenc Zsila, Krzysztof Kamil Bojarski, Tamás Beke-Somfai, Sergey A. Samsonov Journal of Molecular Graphics and Modelling 82 p157-166
Elsevier BV DOI:10.1016/j.jmgm.2018.04.015
Protein–Ligand Interaction Energy-Based Entropy Calculations: Fundamental Challenges For Flexible Systems (2018)
Gergely Kohut, Adam Liwo, Szilvia Bősze, Tamás Beke-Somfai, Sergey A. Samsonov The Journal of Physical Chemistry B 122/32 p7821-7827
American Chemical Society (ACS) DOI:10.1021/acs.jpcb.8b03658

Hemin and bile pigments are the secondary structure regulators of intrinsically disordered antimicrobial peptides (2017)
Ferenc Zsila, Tünde Juhász, Szilvia Bősze, Kata Horváti, Tamás Beke‐Somfai Chirality 30/2 p195-205
Wiley DOI:10.1002/chir.22784
A stretched conformation of DNA with a biological role? (2017)
Niklas Bosaeus, Anna Reymer, Tamás Beke-Somfai, Tom Brown, Masayuki Takahashi, Pernilla Wittung-Stafshede, Sandra Rocha, Bengt Nordén Quarterly Reviews of Biophysics 50
Cambridge University Press (CUP) DOI:10.1017/s0033583517000099
Structural features of human DJ-1 in distinct Cys106 oxidative states and their relevance to its loss of function in disease (2017)
Róbert Kiss, Max Zhu, Balázs Jójárt, András Czajlik, Katalin Solti, Balázs Fórizs, Éva Nagy, Ferenc Zsila, Tamás Beke-Somfai, Gergely Tóth Biochimica et Biophysica Acta (BBA) - General Subjects 1861/11 p2619-2629
Elsevier BV DOI:10.1016/j.bbagen.2017.08.017
Flow Alignment of Extracellular Vesicles: Structure and Orientation of Membrane‐Associated Bio‐macromolecules Studied with Polarized Light (2018)
Imola Cs. Szigyártó, Róbert Deák, Judith Mihály, Sandra Rocha, Ferenc Zsila, Zoltán Varga, Tamás Beke‐Somfai ChemBioChem 19/6 p545-551
Wiley DOI:10.1002/cbic.201700378
Drug and dye binding induced folding of the intrinsically disordered antimicrobial peptide CM15 (2017)
Ferenc Zsila, Szilvia Bősze, Kata Horváti, Imola Cs. Szigyártó, Tamás Beke-Somfai RSC Advances 7/65 p41091-41097
Royal Society of Chemistry (RSC) DOI:10.1039/c7ra05290a

Probing Microscopic Orientation in Membranes by Linear Dichroism (2016)
Sandra Rocha, Maxim Kogan, Tamás Beke-Somfai, Bengt Nordén Langmuir 32/12 p2841-2846
American Chemical Society (ACS) DOI:10.1021/acs.langmuir.5b04229
Ruthenium-Catalyzed Azide Alkyne Cycloaddition Reaction: Scope, Mechanism, and Applications (2016)
Johan R. Johansson, Tamás Beke-Somfai, Anna Said Stålsmeden, Nina Kann Chemical Reviews 116/23 p14726-14768
American Chemical Society (ACS) DOI:10.1021/acs.chemrev.6b00466
Characterization of extracellular vesicles by IR spectroscopy: Fast and simple classification based on amide and C H stretching vibrations (2017)
Judith Mihály, Róbert Deák, Imola Csilla Szigyártó, Attila Bóta, Tamás Beke-Somfai, Zoltán Varga Biochimica et Biophysica Acta (BBA) - Biomembranes 1859/3 p459-466
Elsevier BV DOI:10.1016/j.bbamem.2016.12.005
Dimeric binding of plant alkaloid ellipticine to human serum proteins (2016)
Ferenc Zsila, Tamás Beke-Somfai RSC Advances 6/50 p44096-44105
Royal Society of Chemistry (RSC) DOI:10.1039/c6ra06078a

ATP Hydrolysis in the RecA–DNA Filament Promotes Structural Changes at the Protein–DNA Interface (2015)
Anna Reymer, Sándor Babik, Masayuki Takahashi, Bengt Nordén, Tamás Beke-Somfai Biochemistry 54/30 p4579-4582
American Chemical Society (ACS) DOI:10.1021/acs.biochem.5b00614
Conformational properties of 1,4- and 1,5-substituted 1,2,3-triazole amino acids – building units for peptidic foldamers (2015)
Nina Kann, Johan R. Johansson, Tamás Beke-Somfai Organic & Biomolecular Chemistry 13/9 p2776-2785
Royal Society of Chemistry (RSC) DOI:10.1039/c4ob02359e

Orientation of aromatic residues in amyloid cores: Structural insights into prion fiber diversity (2014)
Anna Reymer, Kendra K. Frederick, Sandra Rocha, Tamás Beke-Somfai, Catherine C. Kitts, Susan Lindquist, Bengt Nordén Proceedings of the National Academy of Sciences 111/48 p17158-17163
Proceedings of the National Academy of Sciences DOI:10.1073/pnas.1415663111
Shear-Induced Membrane Fusion in Viscous Solutions (2014)
Maxim Kogan, Bobo Feng, Bengt Nordén, Sandra Rocha, Tamás Beke-Somfai Langmuir 30/17 p4875-4878
American Chemical Society (ACS) DOI:10.1021/la404857r
UV Transition Moments of Tyrosine (2014)
Louise H. Fornander, Bobo Feng, Tamás Beke-Somfai, Bengt Nordén The Journal of Physical Chemistry B 118/31 p9247-9257
American Chemical Society (ACS) DOI:10.1021/jp5065352
δ‐Peptides from RuAAC‐Derived 1,5‐Disubstituted Triazole Units (2014)
Johan R. Johansson, Elin Hermansson, Bengt Nordén, Nina Kann, Tamás Beke‐Somfai European Journal of Organic Chemistry 2014/13 p2703-2713
Wiley DOI:10.1002/ejoc.201400018

Characterization of the Thermal and Photoinduced Reactions of Photochromic Spiropyrans in Aqueous Solution (2013)
Martin Hammarson, Jesper R. Nilsson, Shiming Li, Tamás Beke-Somfai, Joakim Andréasson The Journal of Physical Chemistry B 117/43 p13561-13571
American Chemical Society (ACS) DOI:10.1021/jp408781p
High anisotropy of flow-aligned bicellar membrane systems (2013)
Maxim Kogan, Bengt Nordén, Tamás Beke-Somfai Chemistry and Physics of Lipids 175-176 p105-115
Elsevier BV DOI:10.1016/j.chemphyslip.2013.08.006
Interactions of a Photochromic Spiropyran with Liposome Model Membranes (2013)
Fabian Jonsson, Tamás Beke-Somfai, Joakim Andréasson, Bengt Nordén Langmuir 29/7 p2099-2103
American Chemical Society (ACS) DOI:10.1021/la304867d
Rate of hydrolysis in ATP synthase is fine-tuned by α-subunit motif controlling active site conformation (2013)
Tamás Beke-Somfai, Per Lincoln, Bengt Nordén Proceedings of the National Academy of Sciences 110/6 p2117-2122
Proceedings of the National Academy of Sciences DOI:10.1073/pnas.1214741110

Energy phase shift as mechanism for catalysis (2012)
Tamás Beke-Somfai, Bobo Feng, Bengt Nordén Chemical Physics Letters 535 p169-172
Elsevier BV DOI:10.1016/j.cplett.2012.03.039
Spectral Properties and Orientation of Voltage-Sensitive Dyes in Lipid Membranes (2012)
Maria Matson, Nils Carlsson, Tamás Beke-Somfai, Bengt Nordén Langmuir 28/29 p10808-10817
American Chemical Society (ACS) DOI:10.1021/la301726w

Exploiting diverse stereochemistry of β-amino acids: toward a rational design of sheet-forming β-peptide systems (2011)
Gábor Pohl, Tamás Beke-Somfai, Imre G. Csizmadia, András Perczel Amino Acids 43/2 p735-749
Springer Science and Business Media LLC DOI:10.1007/s00726-011-1124-7
Double-lock ratchet mechanism revealing the role of αSER-344 in F o F 1 ATP synthase (2011)
Tamás Beke-Somfai, Per Lincoln, Bengt Nordén Proceedings of the National Academy of Sciences 108/12 p4828-4833
Proceedings of the National Academy of Sciences DOI:10.1073/pnas.1010453108
Michler’s Hydrol Blue: A Sensitive Probe for Amyloid Fibril Detection (2011)
Catherine C. Kitts, Tamás Beke-Somfai, Bengt Nordén Biochemistry 50/17 p3451-3461
American Chemical Society (ACS) DOI:10.1021/bi102016p
Flow-alignment of bicellar lipid mixtures: orientations of probe molecules and membrane-associated biomacromolecules in lipid membranes studied with polarized light (2011)
Maxim Kogan, Tamás Beke-Somfai, Bengt Nordén Chemical Communications 47/26 p7356
Royal Society of Chemistry (RSC) DOI:10.1039/c1cc12313k

Structure and Catalysis of Acylaminoacyl Peptidase (2011)
Veronika Harmat, Klarissza Domokos, Dóra K. Menyhárd, Anna Palló, Zoltán Szeltner, Ilona Szamosi, Tamás Beke-Somfai, Gábor Náray-Szabó, László Polgár Journal of Biological Chemistry 286/3 p1987-1998
Elsevier BV DOI:10.1074/jbc.m110.169862
Extended Apolar β-Peptide Foldamers: The Role of Axis Chirality on β-Peptide Sheet Stability (2010)
Gábor Pohl, Tamás Beke, Imre G. Csizmadia, András Perczel The Journal of Physical Chemistry B 114/29 p9338-9348
American Chemical Society (ACS) DOI:10.1021/jp100955u
Zipper-Like Unfolding of β-Sheets Accessed by Pioneer Water Molecules: Atomic Resolution of Forced Unfold Reveals Different Mechanisms for Parallel and Antiparallel Motifs (2010)
Tamás Beke-Somfai, András Perczel The Journal of Physical Chemistry Letters 1/9 p1341-1345
American Chemical Society (ACS) DOI:10.1021/jz100311n

Mechanical Control of ATP Synthase Function: Activation Energy Difference between Tight and Loose Binding Sites (2009)
Tamás Beke-Somfai, Per Lincoln, Bengt Nordén Biochemistry 49/3 p401-403
American Chemical Society (ACS) DOI:10.1021/bi901965c
Chiral and Achiral Fundamental Conformational Building Units of β-Peptides: A Matrix Isolation Conformational Study on Ac-β-HGly-NHMe and Ac-β-HAla-NHMe (2009)
Tamás Beke, Csaba Somlai, Gábor Magyarfalvi, András Perczel, György Tarczay The Journal of Physical Chemistry B 113/22 p7918-7926
American Chemical Society (ACS) DOI:10.1021/jp9022844

Combined NMR three‐bond scalar coupling measurements and QM calculations to calculate OH‐rotamer equilibrium of polyalcohols (2008)
Katalin E. Kövér, Tamás Beke, András Lipták, András Perczel Journal of Computational Chemistry 30/4 p540-550
Wiley DOI:10.1002/jcc.21084
A Theoretical Comparison of Self-Assembling α- and β-Peptide Nanostructures: Toward Design of β-Barrel Frameworks (2008)
Tamás Beke, András Czajlik, Balázs Bálint, András Perczel ACS Nano 2/3 p545-553
American Chemical Society (ACS) DOI:10.1021/nn700252s
Structure and Stability of Short β-Peptide Nanotubes: A Non-Natural Representative of Collagen? (2008)
András Czajlik, Tamás Beke, Andrea Bottoni, András Perczel The Journal of Physical Chemistry B 112/26 p7956-7966
American Chemical Society (ACS) DOI:10.1021/jp7114803

Quantum mechanical studies on the existence of a trigonal bipyramidal phosphorane intermediate in enzymatic phosphate ester hydrolysis (2007)
Imre Berente, Tamás Beke, Gábor Náray-Szabó Theoretical Chemistry Accounts 118/1 p129-134
Springer Science and Business Media LLC DOI:10.1007/s00214-007-0255-0
Major human γ-aminobutyrate transporter: In silico prediction of substrate efficacy (2007)
Anna Palló, Ákos Bencsura, László Héja, Tamás Beke, András Perczel, Julianna Kardos, Ágnes Simon Biochemical and Biophysical Research Communications 364/4 p952-958
Elsevier BV DOI:10.1016/j.bbrc.2007.10.108

Determining suitablelego-structures to estimate stability of larger peptide nanostructures using computational methods (2006)
Tamás Beke, András Czajlik, Imre G Csizmadia, András Perczel Physical Biology 3/1 pS26-S39
IOP Publishing DOI:10.1088/1478-3975/3/1/s04
Theoretical Study on Tertiary Structural Elements of β-peptides: Nanotubes Formed from Parallel-Sheet-Derived Assemblies of β-Peptides (2006)
Tamás Beke, Imre G. Csizmadia, András Perczel Journal of the American Chemical Society 128/15 p5158-5167
American Chemical Society (ACS) DOI:10.1021/ja0585127
Prediction of Folding Preference of 10 kDa Silk-like Proteins Using a Lego Approach and ab Initio Calculations (2006)
Gábor Pohl, Tamás Beke, János Borbély, András Perczel Journal of the American Chemical Society 128/45 p14548-14559
American Chemical Society (ACS) DOI:10.1021/ja063933p

Toward a rational design of β‐peptide structures (2005)
Tamás Beke, Csaba Somlai, András Perczel Journal of Computational Chemistry 27/1 p20-38
Wiley DOI:10.1002/jcc.20299

Potential energy curves, surfaces and hypersurfaces. A model to follow and understand the conformational transformations in amino acids (2004)
András Láng, Anna K Füzéry, Tamás Beke, Péter Hudáky, András Perczel Journal of Molecular Structure: THEOCHEM 675/1-3 p163-175
Elsevier BV DOI:10.1016/j.theochem.2003.12.047

On the flexibility of β‐peptides (2003)
Tamás Beke, Imre G. Csizmadia, András Perczel Journal of Computational Chemistry 25/2 p285-307
Wiley DOI:10.1002/jcc.10357

Peptide models XXXIV. Side-chain conformational potential energy surfaces associated with all major backbone folds of neutral tautomers of N- and C-protected l-histidine. An ab initio study on ethylimidazole and N-formyl-l-histidinamide (2002)
Péter Hudáky, Tamás Beke, András Perczel Journal of Molecular Structure: THEOCHEM 583/1-3 p117-135
Elsevier BV DOI:10.1016/s0166-1280(01)00804-1