@article{93,
  keywords = {FTIR},
  author = {Tamas Bozo and András Wacha and Judith Mihály and Attila Bóta and Miklós Kellermayer},
  title = {Dispersion and stabilization of cochleate nanoparticles},
  abstract = {Abstract Cochleates, calcium-stabilized membrane rolls of nanoscale diameter, promise a unique and efficient way of delivering lipid-soluble drugs, proteins or nucleic acids into biological systems because they protect the encapsulated material against enzymatic or chemical degradation. Self-aggregation, which typically arises during production and storage is a major obstacle that has so far precluded the development of an efficient cochleate-based drug-delivery system. Here we show that citric acid, added transiently in a narrow concentration range, effectively disperses cochleate aggregates, stabilizes the disperse state for long-term storage and preserves the canonical ultrastructure and topological characteristics of cochleate nanoparticles.},
  year = {2017},
  journal = {European Journal of Pharmaceutics and Biopharmaceutics},
  volume = {117},
  pages = {270-275},
  issn = {0939-6411},
  url = {http://www.sciencedirect.com/science/article/pii/S0939641116310074},
  doi = {https://doi.org/10.1016/j.ejpb.2017.04.030},
}