staff:natalia.tokesi [Biological Soft Matter Platform]

Research group	Beke-Somfai Lab: Biomolecular Self-Assembly
Role	Senior researcher
MTMT	10018759

2025
2023
2022
2021
2020
2019
2018
2017
2015
2014
2013
2011
2010
2009
2008
2007
2006
2004

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice (2025)
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi FEBS Open Bio 16/3 p474-486
Wiley DOI:10.1002/2211-5463.70141

Plasma Level of Pyrophosphate Is Low in Pseudoxanthoma Elasticum Owing to Mutations in the ABCC6 Gene, but It Does Not Correlate with ABCC6 Genotype (2023)
Eszter Kozák, Jonas W. Bartstra, Pim A. de Jong, Willem P. T. M. Mali, Krisztina Fülöp, Natália Tőkési, Viola Pomozi, Sara Risseeuw, Jeannette Ossewaarde-van Norel, Redmer van Leeuwen, András Váradi, Wilko Spiering Journal of Clinical Medicine 12/3 p1047
MDPI AG DOI:10.3390/jcm12031047

Cloning and characterization of a novel functional organic anion transporting polypeptide 3A1 isoform highly expressed in the human brain and testis (2022)
Éva Bakos, Orsolya Német, Nóra Kucsma, Natália Tőkési, Bruno Stieger, Elisabeth Rushing, Anna-Mária Tőkés, Péter Kele, Gábor E. Tusnády, Csilla Özvegy-Laczka Frontiers in Pharmacology 13
Frontiers Media SA DOI:10.3389/fphar.2022.958023

Oral supplementation of inorganic pyrophosphate in pseudoxanthoma elasticum (2021)
Eszter Kozák, Krisztina Fülöp, Natália Tőkési, Nidhi Rao, Qiaoli Li, Sharon F. Terry, Jouni Uitto, Xiaoming Zhang, Cyrus Becker, András Váradi, Viola Pomozi Experimental Dermatology 31/4 p548-555
Wiley DOI:10.1111/exd.14498

Creation of the first monoclonal antibody recognizing an extracellular epitope of hABCC6 (2020)
Eszter Kozák, Bence Szikora, Attila Iliás, Péter K. Jani, Zoltán Hegyi, Zsolt Matula, Dóra Dedinszki, Natália Tőkési, Krisztina Fülöp, Viola Pomozi, György Várady, Éva Bakos, Gabor E. Tusnády, Imre Kacskovics, Andras Váradi FEBS Letters 595/6 p789-798
Wiley DOI:10.1002/1873-3468.13991
Pyrophosphate therapy prevents trauma‐induced calcification in the mouse model of neurogenic heterotopic ossification (2020)
Natália Tőkési, Eszter Kozák, Krisztina Fülöp, Dóra Dedinszki, Nikolett Hegedűs, Bálint Király, Krisztián Szigeti, Kitti Ajtay, Zoltán Jakus, Jeremy Zaworski, Emmanuel Letavernier, Viola Pomozi, András Váradi Journal of Cellular and Molecular Medicine 24/20 p11791-11799
Wiley DOI:10.1111/jcmm.15793

Pyrophosphate Treatment in Pseudoxanthoma Elasticum (PXE)-Preventing ReOcclusion After Surgery for Critical Limb Ischaemia (2019)
Suvi Väärämäk, Hannu Uusitalo, Natália Tőkési, Saku Pelttari, András Váradi, Pasi I Nevalainen Surgical Case Reports p1-3
Science Repository OU DOI:10.31487/j.scr.2019.04.02

Dietary Pyrophosphate Modulates Calcification in a Mouse Model of Pseudoxanthoma Elasticum: Implication for Treatment of Patients (2019)
Viola Pomozi, Charnelle B. Julian, Janna Zoll, Kevin Pham, Sheree Kuo, Natália Tőkési, Ludovic Martin, András Váradi, Olivier Le Saux Journal of Investigative Dermatology 139/5 p1082-1088
Elsevier BV DOI:10.1016/j.jid.2018.10.040

Oral administration of pyrophosphate inhibits connective tissue calcification (2017)
Dóra Dedinszki, Flóra Szeri, Eszter Kozák, Viola Pomozi, Natália Tőkési, Tamás Róbert Mezei, Kinga Merczel, Emmanuel Letavernier, Ellie Tang, Olivier Le Saux, Tamás Arányi, Koen van de Wetering, András Váradi EMBO Molecular Medicine 9/11 p1463-1470
Springer Science and Business Media LLC DOI:10.15252/emmm.201707532

Accumulation of the PX domain mutant Frank-ter Haar syndrome protein Tks4 in aggresomes (2015)
Csaba Ádám, Anna Fekete, Gábor Bőgel, Zsuzsanna Németh, Natália Tőkési, Judit Ovádi, Károly Liliom, Szabolcs Pesti, Miklós Geiszt, László Buday Cell Communication and Signaling 13/1
Springer Science and Business Media LLC DOI:10.1186/s12964-015-0108-8

Tubulin acetylation promoting potency and absorption efficacy of deacetylase inhibitors (2014)
V Mangas‐Sanjuan, J Oláh, I Gonzalez‐Alvarez, A Lehotzky, N Tőkési, M Bermejo, J Ovádi British Journal of Pharmacology 172/3 p829-840
Wiley DOI:10.1111/bph.12946
Identification of motives mediating alternative functions of the neomorphic moonlighting TPPP/p25 (2014)
Natália Tőkési, Judit Oláh, Emma Hlavanda, Sándor Szunyogh, Adél Szabó, Fruzsina Babos, Anna Magyar, Attila Lehotzky, Elemér Vass, Judit Ovádi Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1842/4 p547-557
Elsevier BV DOI:10.1016/j.bbadis.2014.01.009

9th EBSA European Biophysics Congress, 13-17 July 2013, Lisbon, Portugal - Abstracts (2013)
European Biophysics Journal 42/S1 p1-236
Springer Science and Business Media LLC DOI:10.1007/s00249-013-0917-x
Moonlighting microtubule‐associated proteins: Regulatory functions by day and pathological functions at night (2013)
J. Oláh, N. Tőkési, A. Lehotzky, F. Orosz, J. Ovádi Cytoskeleton 70/11 p677-685
Wiley DOI:10.1002/cm.21137

Interactions of Pathological Hallmark Proteins (2011)
Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi Journal of Biological Chemistry 286/39 p34088-34100
Elsevier BV DOI:10.1074/jbc.m111.243907

Synthesis and in Vitro Antitumor Effect of Vinblastine Derivative−Oligoarginine Conjugates (2010)
Zoltán Bánóczi, Álmos Gorka-Kereskényi, Judit Reményi, Erika Orbán, László Hazai, Natália Tőkési, Judit Oláh, Judit Ovádi, Zoltán Béni, Viktor Háda, Csaba Szántay, Ferenc Hudecz, György Kalaus, Csaba Szántay Bioconjugate Chemistry 21/11 p1948-1955
American Chemical Society (ACS) DOI:10.1021/bc100028z
TPPP/p25 Promotes Tubulin Acetylation by Inhibiting Histone Deacetylase 6 (2010)
Natália Tőkési, Attila Lehotzky, István Horváth, Bálint Szabó, Judit Oláh, Pierre Lau, Judit Ovádi Journal of Biological Chemistry 285/23 p17896-17906
Elsevier BV DOI:10.1074/jbc.m109.096578

Tubulin polymerization‐promoting protein (TPPP/p25) is critical for oligodendrocyte differentiation (2009)
Attila Lehotzky, Pierre Lau, Natália Tőkési, Naser Muja, Lynn D. Hudson, Judit Ovádi Glia 58/2 p157-168
Wiley DOI:10.1002/glia.20909

Unique pharmacology of KAR-2, a potential anti-cancer agent: Absorption modelling and selective mitotic spindle targeting (2009)
Isabel Gonzalez-Alvarez, Marta Gonzalez-Alvarez, Davinia Oltra-Noguera, Virginia Merino, Natália Tõkési, Judit Ovádi, Marival Bermejo European Journal of Pharmaceutical Sciences 36/1 p11-19
Elsevier BV DOI:10.1016/j.ejps.2008.10.020
Progress in the development of early diagnosis and a drug with unique pharmacology to improve cancer therapy (2008)
A Lehotzky, N Tőkési, I Gonzalez-Alvarez, V Merino, M Bermejo, F Orosz, P Lau, G.G Kovacs, J Ovádi Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 366/1880 p3599-3617
The Royal Society DOI:10.1098/rsta.2008.0106

Phosphorylation Blocks the Activity of Tubulin Polymerization-promoting Protein (TPPP) (2007)
Emma Hlavanda, Eva Klement, Endre Kókai, János Kovács, Orsolya Vincze, Natália Tőkési, Ferenc Orosz, Katalin F. Medzihradszky, Viktor Dombrádi, Judit Ovádi Journal of Biological Chemistry 282/40 p29531-29539
Elsevier BV DOI:10.1074/jbc.m703466200
Unconventional translation initiation of human trypsinogen 4 at a CUG codon with an N‐terminal leucine (2007)
Attila L. Németh, Péter Medveczky, Júlia Tóth, Erika Siklódi, Katalin Schlett, András Patthy, Miklós Palkovits, Judit Ovádi, Natália Tõkési, Péter Németh, László Szilágyi, László Gráf The FEBS Journal 274/6 p1610-1620
Wiley DOI:10.1111/j.1742-4658.2007.05708.x

Interaction of TPPP/p25 protein with glyceraldehyde‐3‐phosphate dehydrogenase and their co‐localization in Lewy bodies (2006)
Judit Oláh, Natália Tőkési, Orsolya Vincze, István Horváth, Attila Lehotzky, Anna Erdei, Emília Szájli, Katalin F. Medzihradszky, Ferenc Orosz, Gábor G. Kovács, Judit Ovádi FEBS Letters 580/25 p5807-5814
Wiley DOI:10.1016/j.febslet.2006.09.037
Tubulin Polymerization Promoting Proteins (TPPPs): Members of a New Family with Distinct Structures and Functions (2006)
Orsolya Vincze, Natália Tökési, Judit Oláh, Emma Hlavanda, Ágnes Zotter, István Horváth, Attila Lehotzky, László Tirián, Katalin F. Medzihradszky, János Kovács, Ferenc Orosz, Judit Ovádi Biochemistry 45/46 p13818-13826
American Chemical Society (ACS) DOI:10.1021/bi061305e

Dynamic targeting of microtubules by TPPP/p25 affects cell survival (2004)
Atilla Lehotzky, László Tirián, Natália Tökési, Péter Lénárt, Bálint Szabó, János Kovács, Judit Ovádi Journal of Cell Science 117/25 p6249-6259
The Company of Biologists DOI:10.1242/jcs.01550

Natália Tőkési

List of publications