Monolith NT.Automated Microscale Thermophoresis Instrument
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| Research group | Beke-Somfai Lab: Biomolecular Self-Assembly |
| Contact person | Tünde Juhász |
| Technique | Microscale Thermophoresis |
| Make & model | NanoTemper Monolith.NT Automated |
Summary
MicroScale Thermophoresis (MST) is an easy, fast, and precise way to quantify biomolecular interactions. It measures the motion of molecules along microscopic temperature gradients and detects changes in their hydration shell, charge or size. The applications range from small molecule binding events to interactions of multi-component systems. The automated setup allows for high-throughput applications. Our Monolith NT.Automated device is equipped with nano-blue and pico-red detection systems.
Example results
Characterization of biomolecular interactions
- Binding assays on labeled peptides with small molecule agents, liposomes, etc
- Binding assays on labeled vesicles with small molecules, peptides, proteins, etc.